Our Science
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Disruptive and challenges existing dogma targeting amyloid
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Focused on identifying the pivotal basic mechanism, driven by a 14mer peptide
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Asks why only certain cells are primarily vulnerable in AD, so their special properties can be explored for potential manipulation
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Suggests a novel theory of AD (Garcia-Ratés, et al 2024) where neurodegeneration is an aberrant form of development that if activated only in a key group of cells it turns toxic in a mature brain
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Accounts for all the known clinical facts e.g. time lag for cognitive symptoms, co-pathology with Parkinson’s Disease, and selective neuronal vulnerability
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It leads to other disorders such as cancer, skin disorders and diabetic retinopathy.
Neuro-Bio discovery of the biology of 14mer peptide leads to the development of 2 strategies:
