Our team has demonstrated that oxidative stress, triggered by high glucose, increases T14 peptide levels in vitro and reduces cell viability. The cyclic form of T14, NBP14, blocked these toxic effects, suggesting its potential as a therapeutic agent. These findings highlight that oxidative stress could activate T14 in the adult brain through AChE upregulation, contributing to neurodegeneration in Alzheimer’s disease.
LATEST NEWS
- Neuro-Bio new publication – Oxidative Stress Triggers a Pivotal Peptide Linked to Alzheimer’s Disease
- Neuro-Bio is joining the newly formed Employer Advisory Board at Nottingham Trent University and the Biosciences Department
- Baroness Greenfield is speaking at the Brain Innovation Day Conference in Brussels – November 2024!
- Baroness Greenfield speaks at the Longevity Nation 2024 Conference – October 2024!
- Baroness Greenfield speaks at the House of Lords debates on the contribution of science and technology to the UK economy