Neuro-Bio new publication – Oxidative Stress Triggers a Pivotal Peptide Linked to Alzheimer’s Disease

Our team has demonstrated that oxidative stress, triggered by high glucose, increases T14 peptide levels in vitro and reduces cell viability. The cyclic form of T14, NBP14, blocked these toxic effects, suggesting its potential as a therapeutic agent. These findings highlight that oxidative stress could activate T14 in the adult brain through AChE upregulation, contributing to neurodegeneration in Alzheimer’s disease.

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